Comparison of effect of parenteral and oral supplementation of Selenium and vitamin E on selected antioxidant parameters and udder health of dairy cows

Journal title

Polish Journal of Veterinary Sciences




vol. 25


No 1


Vasiľ, M. : Department of Nutrition and Animal Husbandry, University of Veterinary Medicine and Pharmacy in Kosice, Komenského 73, Košice, 04001, Slovakia ; Zigo, F. : Department of Nutrition and Animal Husbandry, University of Veterinary Medicine and Pharmacy in Kosice, Komenského 73, Košice, 04001, Slovakia ; Farkašová, Z. : Department of Nutrition and Animal Husbandry, University of Veterinary Medicine and Pharmacy in Kosice, Komenského 73, Košice, 04001, Slovakia ; Pecka-Kielb, E. : Department of Biostructure and Animal Physiology, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375 Wroclaw, Poland ; Bujok, J. : Department of Biostructure and Animal Physiology, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375 Wroclaw, Poland ; Illek, J. : Large Animal Clinical Laboratory, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences, Palackého tř. 1946/1, 612 42 Brno, Czech Republic



dairy cows ; calving ; colostrum ; glutathione peroxidase ; milk malondialdehyde ; mastitis

Divisions of PAS

Nauki Biologiczne i Rolnicze




Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn


Andrei S, Matei S, Fit N, Cernea C, Ciupe S, Bogdan S, Groza IS (2011) Glutathione peroxidase activity and its relationship with somatic cell count, number of colony forming units and protein content in subclinical mastitis cow’s milk. Rom Biotechnol Letters 16: 6209-6217.
Andrei S, Matei S, Rugina D, Bogdan L, Stefanut C (2016) Interrelationships between the content of oxidative markers, antioxidative status, and somatic cell count in cow’s milk. Czech J Anim Sci 61: 407-413.
AOAC, Associatition of Official Analytical Chemists Interntional (2001) Official methods of analysis. 17th ed., Horwitz W. (ed): AOAC Inc., Arlington, USA, ISBN 0-935584-42-0.
Bouwstra RJ, Nielen M, Stegeman JA, Dobbelaar P, Newbold JR, Jansen EHJM, Van Werven T (2010) Vitamin E supplementation during the dry period in dairy cattle. Part 1: Adverse effect on incidence of mastitis postpartum in a double-blind randomized field trial. J Dairy Sci 93: 5684-5695.
Bujňák L, Maskaľová I, Vajda V (2011) Determination of buffering capacity of selected fermented feedstuffs and the effect of dietary acid-base status on ruminal fluid pH. Acta Vet Brno 80: 269-273.
Castillo C, Hernandez J, Valverde I, Pereira V, Sotillo J, Alonso M, Benedito JL (2006) Plasma malondialdehyde (MDA) and total antioxidant status (TAS) during lactation in dairy cows. Res Vet Sci 80: 133-139.
Cohen RD, King BD, Guenther C, Janzen ED (1991) Effect of pre-partum parenteral supplementation of pregnant beef cows with selenium/vitamin E on cow and calf plasma selenium and productivity. Can Vet J 32: 113-115.
Grešáková L, Čobanová K, Faix S (2013) Selenium retention in lambs fed diets supplemented with selenium from inorganic sources. Small Rumin Res 111: 76-82.
Hawari AD, Al-Dabbas F (2008) Prevalence and distribution of mastitis pathogens and their resistance against antimicrobial agents in dairy cows in Jordan. Am J Anim Vet Sci 3: 36-39.
Hess D, Keller HE, Oberlin B, Bonfanti R, Schüep W (1991) Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of high-performance liquid chromatography on reversed phase. Int J Vitam Nutri Res 61: 232-238. https://pubmed.ncbi.nlm.
Hoque MN, Das ZC, Rahman AN, Hoque MM (2016) Effect of administration of vitamin E, selenium and antimicrobial therapy on incidence of mastitis, productive and reproductive performances in dairy cows. International J Vet Sci Med 4: 63-70.
Jackson P, Cockcroft P (2002) Clinical examination of farm animals. Blackwell Science Ltd Oxford, UK, ISBN 0-632-05706-8, pp 154-166.
Kafilzadeh F, Kheirmanesh H, ShabankarehHK, Targhibi MR, Maleki E, Ebrahimi M, Meng GY, (2014) Comparing the effect of oral supplementation of vitamin E, injective vitamin E and selenium or both during late pregnancy on production and reproductive performance and immune function of dairy cows and calves. Scientific World Journal, 2014, Article ID 1658415.
Khatti A, Mehrotra S, Patel PK, Singh G., Maurya VP, Mahla AS, Chaudhari RK, Das GK, Singh M., Sarkar M., Kumar Z, Krysznaswamy HN (2017) Supplementation of vitamin E, selenium and increased energy allowance mitigates the transition stress and improves postpartum reproductive performance in the crossbred cow. Theriogenology 104: 142-148.
Kommisrud E, Österas O, Vatn T (2005) Blood Selenium associated with health and fertility in Norvegian dairy herds. Acta Vet Scand 46: 229-240.
Liu F, Cottrell JJ, Furness JB,Rivera RL, Kelly FW, Wijesiriwardana U, Pustovit RV, Fothergill LJ, Bravo DM, Celi P, Leury BJ, Gabler MK, Dunshea FR (2016) Selenium and vitamin E together improve intestinal epithelial barrier function and alleviate oxidative stress in heat-stressed pigs. Exp Physiol. 101: 801-810.
Meglia GE, Jensen SK, Lauridsen C, Waller KP (2006) a-Tocopherol concentration and stereoisomer composition in plasma and milk from dairy cows fed natural or synthetic vitamin E around calving. J Dairy Res 73: 227-234.
Mehdi Y, Dufrasne I (2016) Selenium in Cattle: A Review. Molecules 21: 545.
National Mastitis Council (2001) National Mastitis Council Recommended Mastitis Control Program.
Nutrient requirements of dairy cattle, NRC (2001) National Academy Press, Washington, DC, USA, 7th ed. O’Rourke D (2009) Nutrition and udder health in dairy cows: a review. Irish Vet J 62 (Suppl 4): 15-20.
Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erytrocyte glutathione peroxidase. Journal Lab Clin Med 70: 158-169.
Pavlata L, Illek J, Pechova A, Matejiček M (2002) Selenium Status of Cattle in the Czech Republic, Acta Vet. Brno 71: 3-8.
Pavlata L, Prasek J, Filipek A, Pechova A, (2004a) Influence of parenteral administration of selenium and vitamin E during pregnancy on selected metabolic parameters and colostrum quality in dairy cows at parturition. Vet Med Czech 49: 149-155.
Pavlata L, Podhorsky A, Pechova A, Dvorak R (2004b) Incidence of hypovitaminosis E in calves and therapeutic remedy by selenium-vitamin supplementation. Acta Vet. Brno 74: 209-216.
Pechova A, Pavlata L, Illek J (2005) Blood and tissue selenium determination by hydride generation atomic absorption spectrophotometry. Acta Vet. Brno 74: 483-490.
Waller PK, Hallen SC, Emanuelson U, Jensen SK (2007) Supplementation of RRR-alpha-tocopheryl acetate to periparturient dairy cows in commercial herds with high mastitis incidence. J Dairy Sci 90: 3640-3646.
Scholz H, Stober M (2002) Enzootic myodystrophia in preruminant calves. Inter Med and Sur in Cattle (in German). Parey Buchverlag, Berlin 1000-1004.
Sharma N, Singh NK, Singh OP, Pandey V, Verma PK (2011) Oxidative stress and antioxidant status during transition period in dairy cows. Asian-Austr J Anim Sci 24: 479-484.
Smith KL, Hogan JS, Weiss WP (1997) Dietary vitamin E and selenium affect mastitis and milk quality. J Anim. Sci 75: 1659-1665.
Spears JW, Weiss WP (2008) Role of antioxidants and trace elements in health and immunity of transition dairy cows. Vet J Sci 176: 70-76.
Turk R, Koledic M, Macesic N, Benic M, Dobranic V, Duricic D, Urbani A, Mestric ZF, Soggiu A, Bonizzi L, Roncada P (2017) The role of oxidative stress and inflammatory response in the pathogenesis of mastitis in dairy cows. Mljekarstvo 67: 91-101.
Zigo F, Vasil’ M, Ondrašovičová, S, Výrostková J, Bujok J, Pecka-Kielb E (2021) Maintaining optimal mammary gland health and prevention of mastitis. Front. Vet. Sci. 8: 607311.






DOI: 10.24425/pjvs.2022.140852